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Then stereotaxic injections were performed bilaterally, to target descending noradrenergic brainstem populations in the locus coeruleus, ventro-lateral pons, and the ventro-medial rostral medulla

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A whole of 19 L of AAV was injected into each animal employing a...
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When expressed in 3T3 cells or in major neurons, we noticed a palmitoylation-dependent affiliation of MAP6d1 with the Golgi apparatus and the plasma membrane. In addition, we can also observed MAP6d1 interaction with mitochondria through its N-terminal area, independently of its palmitoylation

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And finally, we show that MAP6d1 can multimerize by using its microtubule-binding module Mn....
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This is probably brought about by the diminished number of readily available downstream J segments ensuing from J1 skipping because of to premature J2 breaks, which illustrates the value of the non-stochastic 5′-3′ purchase of J rearrangements

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These scores are constant with the biased utilization of J segments in main rearrangements...
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. The presence of insoluble stored glycogen articles in the trans-differentiated cells was assessed by periodic acid Schiff’s (PAS) staining, for which the cells at times 28 and 35 ended up set with four% paraformaldehyde for thirty minutes

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To date, however, a few investigations have been accomplished on the possible use of...