This is known to convert IRS-1 into an inhibitor of the insulin receptor tyrosine kinase
tment, although inhibition of HSP47 expression alone failed to induce the morphological change. SB-366791...
The ratios were then compared between control and PD173074-treated animals
ents for efficacy in reversing or preventing T1D in rodents. NIDDK issued a Request...
The GST tag was then removed using Prescission protease
odels of type 1 diabetes mimic many of the pathogenic processes involved in disease...
Cells were induced with the indicated reagents at 24 h after transfection
Closed c-Src , 1:10,000 for a-tubulin. The membrane was then washed four times over...
All seven analyzed samples showed increased DNA methylation of the KRT19 promoter
al was harvested for AECII according to our previously published protocol, or removed from...
Briefly, the MSCs were cultured in 4-well glass plates and incubated for 24 h
e near the Ca2+-bowl of the BKCa channel a subunit to alter Ca2+ sensing....
In our study, osmotic shock was shown to increase echinocandin-mediated lysis
nd mock 11733457 PE/CA-PJ15 cells were subcutaneously injected on the left and right backs...
Specifically, miR-133b directly impairs the expression of important antiapoptotic genes
l. found that the TLR4-p38 MAPK-CREB axis is responsible for PAI-2 induction by searching...
To further address the specificity of this pT120 antibody, we performed peptide competition assay
ute wortmanin pre-treatment. Similar downregulation of Dnmt3A and Dnmt3L gene expression was observed in...
These proteins allow for the passive diffusion of solutes across the outer membrane
owed significantly 44%, 28% and 61% lower cell binding and thus decreasing internalization by...