Ing a LEGENDplex assay in plasma from malaria individuals and manage individuals and in culture supernatant of endothelial cells (HBEC-5i) stimulated with these plasmas. Table S4–Levels of TNF- in plasma from malaria individuals and handle individuals. Table S5–Adjustment for a number of comparison (cutoffs which are met for the corresponding analyte are shown in bolt). Table S6–Levels of ANGPTL4 in plasma from malaria patients and handle men and women and in culture supernatant of endothelial cells (HEBEC-5i) stimulated with these plasmas. Table S7–Levels of cytokines inside the plasma of 3 control men and women (H5, H8, H10) and of 4 malaria Ubiquitin-Specific Protease 13 Proteins Purity & Documentation sufferers (M6, M9, M10, M11), which had been utilised to stimulated endothelial cells (HBEC-5i) for transcriptome evaluation. Table S8–Levels of cytokines inside the culture supernatant of endothelial cells (HBEC-5i), stimulated with plasma of 3 control men and women (H5, H8, H10) and of four malaria individuals (M6, M9, M10, M11). Table S9–Transcriptome analyses of endothelial cells (HBEC-5i) stimulated with plasma from three healthy handle men and women (H5, H10, H8) and from four malaria sufferers (M6, M9, M10, M11). Table S10–Genes whose expression is drastically decreased following co-incubation of endothelial cells (HBEC-5i) with plasma from malaria individuals (M) when compared with the healthy controls (H). Table S11–Genes whose expression is drastically improved after co-incubation of endothelial cells (HBEC-5i) with plasma from malaria individuals (M) in comparison to the healthier controls (H). Author Contributions: Conceptualization, M.R., M.D. and I.B.; methodology, M.R., A.K., M.D., C.F. and T.J.; computer software, S.L. and I.B.; validation, M.R. and I.B.; formal evaluation, M.R., A.K. and I.B.; investigation, M.R., A.K., M.D., J.B., Y.W. and C.F.; writing–original draft preparation, M.R. and I.B.; writing–review and editing, M.R., J.S., T.J., A.B., T.R., N.G.M. and I.B.; supervision, I.B., funding acquisition, M.D. and I.B. All authors have study and agreed for the published version from the manuscript. Funding: This investigation was funded by J gen Manchot Stiftung (M.D.), German Center for Infec tion Research (DZIF) (M.R.), Leibniz Center Infection (J.B.) and Chinese Scholarship Council (Y.W.). The publication of this short article was funded by the Open Access Fund from the Leibniz Association. Institutional Review Board Statement: The study was performed according to the recommendations in the Declaration of Helsinki, and approved by the relevant ethics committee: Ethical Assessment Board of your Medical Association of Hamburg, Germany; reference numbers PV3828 and PV4539. Informed Consent Statement: Not applicable. Information Availability Statement: Data is contained within this short article and corresponding supplementary material. Acknowledgments: We thank Ulricke Richardt and Susann Ofori for fantastic technical assistance. Conflicts of Interest: The authors declare no conflict of interest.
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