Outcome. A handful of sufferers with an initial low GCS do recover fully.P246 Factors influencing the functional outcome inside a neurointensive care unitE Anastasiou, A Euthimiou, A Lavrentieva, G Tsaousi, E Geka, M Yannakou Intensive Care Unit of Anesthesiology, AHEPA Basic University Hospital, Nelociguat site Thessaloniki, Greece Introduction: The aim in the present study was to investigate the elements that affect the outcome of individuals with central nervous program pathology. Process: 1 hundred and thirty patients (head injury [n = 43], several trauma [n = 40], cerebral hemorrhage [n = 36] and emergency cerebral aneurysm repair [n = 11]) have been investigated for age, GCS, CT-Scan grade, ISS, and APACHE II. Male to female ratio was 96/34. The sufferers were divided in five groups as outlined by Glasgow Outcome Scale: 1) group A, n = 50 (GOS 1, death), 2) group B, n = 5 (GOS two, serious brain harm), 3) group C, n = 17 (GOS 3, moderate brain damage), 4) group D, n = 28 (GOS four, mild disability) and five) group E, n = 30 (GOS five, complete recovery).TableAge (years)Benefits: Total mortality was 38.four . There was a statistically significant difference (one way analysis of variance ANOVA) relating to: 1) age: groups A, B and C versus E, two) GCS: group A versus E, three) CT-Scan grade: group A versus D and E, 4) ISS: group C versus D and E and 5) APACHE II score: group C versus E (Table). Patients with head injury or several trauma had better outcome than patients with cerebral hemorrhage (Fig.). Conclusion: Age, GCS and CT-Scan grade had been related for the patient outcome regarding life or death whereas diagnosis, age, ISS and APACHE II determined the severity of disability.FigureGroups A B C D EGCSCT-Scan grade three.five ?0.5* 3.2 ?0.eight 3 ?0.eight 2.7 ?0.7 two.eight ?0.ISS 29.1 ?9.3 25 ?APACHE II 19.9 ?four.5 15.6 ?6.42.3 ?17.5** 53 ?20.8* 43.7 ?19.7* 37.six ?16.2 28.2 ?15.six.1 ?2.5* five.8 PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20719582 ?1.0 6.6 ?3.0 7.0 ?three.1 8.2 ?three.36.six ?8.3* 21.5 ?four.5* 24.six ?six.1 26.1 ?8.2 18.4 ?4.8 16.9 ?four.Relation of diagnosis to GOSMean ?SD. * P < 0.05, ** P < 0.01.P247 Prolonged intensive care unit stay: predictors and impact on resource utilizationS Haddad, Y Arabi, R Goraj, A Al-Shimemeri Intensive Care Department 1425, PO Box 22490, King Fahad National Guard Hospital, Riyadh 11426, Saudi Arabia Objective: To evaluate the predictors of prolonged ICU stay its impact on resource utilization. Methods: We collected the following data prospectively on all ICU admissions between 2/1999 and 9/2000: demographics, ICU stay, APACHE II and SAPS II scores, the main reason for ICU admission, re-admissions and ICU outcome. We documented the presence of coma, oliguria, coagulopathy and infection as well as the need for mechanical ventilation or vasopressors in the first 24 hours. ICU stay was considered prolonged if it exceeded 14 days. We calculated the utilization of ICU days and ventilator days. We identified predictors of prolonged stay using univariate analysis. Results: Eleven percent of patients (104/947) stayed in ICU > 14 days. This group of patients utilized 45 (2880/6392) of ICU days and 56 (2556/4604) of ventilation days. Prolonged remain patients had higher APACHE II (21 ?8 vs 19 ?9, P = 0.016) and SAPS II scores (43 ?16 vs 37 ?20, P = 0.003), although ICU mortality was not various (19 vs 21 ). Patients had been more probably to possess prolonged stay if the major purpose for admission was respiratory (OR 2.2, CI 1.four?.6) or trauma (OR 2.1, CI 1.4?.4) and much less probably if it was non-trauma surgical (OR 0.27, CI 0.13?.54). Prolonged keep occurred a lot more l.