And to older children and young adults in order to ascertain longer term outcomes. A dearth of research on acquired language disorders in children was also noted. A related set of issues surround co-occurring conditions (or comorbidities). It was widely held that language difficulties are often associated with behavioural problems but we are only starting to understand the causal relationships [121]. The relationship between language difficulties and autism spectrum disorder on the one hand and intellectual disability on the other hand generated many free text comments from our panellists and it is clear that more and better research is needed. Arguably the same can be said for co-occurring motor disorders and executive impairments (notably working memory problems). Our panel also made clear that progress would be limited until more reliable and valid assessment methods are developed. The current consensus is that we lack suitable tools for early identification of children at risk of longer-term language impairment: development of methods for distinguishing transient from persistent language problems should be a priority. In addition, further work needs to be done to develop methods for evaluating functional impact of language impairment–that is assessments which go beyond specifying severity in statistical terms. Methods for reliable assessment of pragmatic difficulties are urgently required. There was also interest in identifying developmental trajectories or profiles that would aid differential diagnosis. In this regard, it is Anlotinib biological activity timely to make comparisons between different neurodevelopmental disorders [97]. Aside from psychometric concerns, there were two important issues which particularly affect professionals working in education. First, how to conceptualise the relationship between poor socioeconomic circumstances and language impairment and second, how to identify a language impairment in a child whose first (and often home) language is not English. Both of these issues underline the need for multicultural research perspectives in future research and the importance of developing assessments which mirror classroom demands. Moreover, there were cogent arguments for research into the use of dynamic assessment methods which are culture-fair, in particular to inform decisions regarding intervention. Together these research gaps comprise a significant research agenda. They also underline the fact that language difficulties are heterogeneous and much that has been learnt from studying children with relatively `pure’ disorders will need to be modified in the light of recent developments in theory and practice. There is, it was argued, a duty on editorial boards of journals to ensure that samples of children with language difficulties are described fully; we need to know not only what the inclusion and exclusion criteria are, and whether there was any assessment for co-occurring conditions such as speech, attentional or motor problems. We should not restrict research to those with no co-occurring problems, but we do need to know whether they are present and affect language profiles. Development of a standard checklist for reporting participant characteristics could make it easier to compare and combine information across studies.EducationGiven the complexity of language impairment and co-occurring difficulties such as MLN9708 chemical information speech disorders, social impairments and reading disorders, there is an urgent need for better information and training [12.And to older children and young adults in order to ascertain longer term outcomes. A dearth of research on acquired language disorders in children was also noted. A related set of issues surround co-occurring conditions (or comorbidities). It was widely held that language difficulties are often associated with behavioural problems but we are only starting to understand the causal relationships [121]. The relationship between language difficulties and autism spectrum disorder on the one hand and intellectual disability on the other hand generated many free text comments from our panellists and it is clear that more and better research is needed. Arguably the same can be said for co-occurring motor disorders and executive impairments (notably working memory problems). Our panel also made clear that progress would be limited until more reliable and valid assessment methods are developed. The current consensus is that we lack suitable tools for early identification of children at risk of longer-term language impairment: development of methods for distinguishing transient from persistent language problems should be a priority. In addition, further work needs to be done to develop methods for evaluating functional impact of language impairment–that is assessments which go beyond specifying severity in statistical terms. Methods for reliable assessment of pragmatic difficulties are urgently required. There was also interest in identifying developmental trajectories or profiles that would aid differential diagnosis. In this regard, it is timely to make comparisons between different neurodevelopmental disorders [97]. Aside from psychometric concerns, there were two important issues which particularly affect professionals working in education. First, how to conceptualise the relationship between poor socioeconomic circumstances and language impairment and second, how to identify a language impairment in a child whose first (and often home) language is not English. Both of these issues underline the need for multicultural research perspectives in future research and the importance of developing assessments which mirror classroom demands. Moreover, there were cogent arguments for research into the use of dynamic assessment methods which are culture-fair, in particular to inform decisions regarding intervention. Together these research gaps comprise a significant research agenda. They also underline the fact that language difficulties are heterogeneous and much that has been learnt from studying children with relatively `pure’ disorders will need to be modified in the light of recent developments in theory and practice. There is, it was argued, a duty on editorial boards of journals to ensure that samples of children with language difficulties are described fully; we need to know not only what the inclusion and exclusion criteria are, and whether there was any assessment for co-occurring conditions such as speech, attentional or motor problems. We should not restrict research to those with no co-occurring problems, but we do need to know whether they are present and affect language profiles. Development of a standard checklist for reporting participant characteristics could make it easier to compare and combine information across studies.EducationGiven the complexity of language impairment and co-occurring difficulties such as speech disorders, social impairments and reading disorders, there is an urgent need for better information and training [12.