Product Name :
Glycyl H-1152 hydrochloride
Description:
Glycyl H-1152 hydrochloride (compound 18) is a glycyl derivative of Rho-kinase inhibitors H-1152 dihydrochloride. Glycyl H-1152 hydrochloride inhibits ROCKII, Aurora A, CAMKII and PKG, with IC50s of 0.0118, 2.35, 2.57 and 3.26 μM respectively. Glycyl H-1152 hydrochloride has higher selective than H-1152 hydrochloride.
CAS:
913844-45-8
Molecular Weight:
449.40
Formula:
C18H26Cl2N4O3S
Chemical Name:
2-amino-1-[(3S)-3-methyl-4-[(4-methylisoquinolin-5-yl)sulfonyl]-1,4-diazepan-1-yl]ethan-1-one dihydrochloride
Smiles :
Cl.Cl.CC1=CN=CC2=CC=CC(=C12)S(=O)(=O)N1CCCN(C[C@@H]1C)C(=O)CN
InChiKey:
ILDBNQGLZFSHQZ-UTLKBRERSA-N
InChi :
InChI=1S/C18H24N4O3S.2ClH/c1-13-10-20-11-15-5-3-6-16(18(13)15)26(24,25)22-8-4-7-21(12-14(22)2)17(23)9-19;;/h3,5-6,10-11,14H,4,7-9,12,19H2,1-2H3;2*1H/t14-;;/m0../s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Glycyl H-1152 hydrochloride (compound 18) is a glycyl derivative of Rho-kinase inhibitors H-1152 dihydrochloride. Glycyl H-1152 hydrochloride inhibits ROCKII, Aurora A, CAMKII and PKG, with IC50s of 0.0118, 2.35, 2.57 and 3.26 μM respectively. Glycyl H-1152 hydrochloride has higher selective than H-1152 hydrochloride.|Product information|CAS Number: 913844-45-8|Molecular Weight: 449.40|Formula: C18H26Cl2N4O3S|Chemical Name: 2-amino-1-[(3S)-3-methyl-4-[(4-methylisoquinolin-5-yl)sulfonyl]-1,4-diazepan-1-yl]ethan-1-one dihydrochloride|Smiles: Cl.Cl.CC1=CN=CC2=CC=CC(=C12)S(=O)(=O)N1CCCN(C[C@@H]1C)C(=O)CN|InChiKey: ILDBNQGLZFSHQZ-UTLKBRERSA-N|InChi: InChI=1S/C18H24N4O3S.{{Saquinavir} medchemexpress|{Saquinavir} Autophagy|{Saquinavir} Biological Activity|{Saquinavir} In Vivo|{Saquinavir} manufacturer|{Saquinavir} Autophagy} 2ClH/c1-13-10-20-11-15-5-3-6-16(18(13)15)26(24,25)22-8-4-7-21(12-14(22)2)17(23)9-19;;/h3,5-6,10-11,14H,4,7-9,12,19H2,1-2H3;2*1H/t14-;;/m0.{{Verteporfin} medchemexpress|{Verteporfin} Autophagy|{Verteporfin} Biological Activity|{Verteporfin} Purity|{Verteporfin} custom synthesis|{Verteporfin} Epigenetics} .PMID:23577779 /s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
