T; accessible in PMC 2015 June 01.Knelson et al.PageAcknowledgmentsWe thank Angela L. Gaviglio for crucial reading of this manuscript. This function was supported in part by NIH grants F30 CA168043-01 (EHK), R01-CA136786 (GCB), and R01-CA135006 (GCB), at the same time as a Reach Award from Alex’s Lemonade Stand.NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author Manuscript
Nutrients 2013, 5, 1169-1185; doi:ten.3390/nuOPEN ACCESSnutrientsISSN 2072-6643 www.mdpi/journal/nutrients ReviewDietary Sources of Lutein and Zeaxanthin Carotenoids and Their Role in Eye HealthEl-Sayed M. Abdel-Aal 1,*, Humayoun Akhtar 1, Khalid Zaheer two and Rashida Ali 3,2Guelph Meals Research Centre, Agriculture and Agri-Food Canada, Guelph, ON N1G 5C9, Canada; E-Mail: [email protected] Consultant, Toronto, ON M3M 2E9, Canada; E-Mail: kzaheer2000@gmail Department of Food Science and Technologies, ICCBS, University of Karachi, Karachi 75270, Pakistan; E-Mail: rashida338@gmail English Biscuit Suppliers Pvt. Ltd., Korangi Industrial Location, Karachi 74900, Pakistan* Author to whom correspondence ought to be addressed; E-Mail: [email protected]; Tel.: +1-226-217-8079; Fax: +1-226-217-8181. Received: 2 February 2013; in revised type: 21 March 2013 / Accepted: 26 March 2013 / Published: 9 AprilAbstract: The eye is usually a significant sensory organ that demands particular care for a healthful and productive life-style. Various studies have identified lutein and zeaxanthin to be crucial elements for eye overall health. Lutein and zeaxanthin are carotenoid pigments that impart yellow or orange color to various prevalent foods like cantaloupe, pasta, corn, carrots, orange/yellow peppers, fish, salmon and eggs.Carbamazepine Their function in human well being, in unique the health of the eye, is well established from epidemiological, clinical and interventional studies. They constitute the key pigments located within the yellow spot on the human retina which protect the macula from damage by blue light, boost visual acuity and scavenge damaging reactive oxygen species. They have also been linked with decreased threat of age-related macular degeneration (AMD) and cataracts. Investigation more than the previous decade has focused on the development of carotenoid-rich foods to boost their intake particularly within the elderly population. The aim of this short article would be to overview current scientific evidences supporting the rewards of lutein and zexanthin in stopping the onset of two key age-related eye illnesses with diets rich in these carotenoids.Karanjin The critique also lists important dietary sources of lutein and zeaxanthin and refers to newly developed foods, each day intake, bioavailability and physiological effects in relation to eye health.PMID:24293312 Examples on the newly created high-lutein functional foods are also underlined.Nutrients 2013, five Key phrases: lutein and zeaxanthin carotenoids; dietary sources; eye health; high-lutein foods; bioavailability1. Introduction Nutrition plays a very important part in human health with no exception for the eye. Healthier eyes offer excellent vision, that is critical for an enjoyable and productive life style. There is a growing global concern about eye wellness associated challenges. To address these challenges the Planet Health Organization (WHO) report on visual impairment in 2010 identifies the principal causes of visual impairment as follows: uncorrected refractive errors (43 ), cataracts (33 ), glaucoma (2 ), age-related macular degeneration (AMD) (1 ), diabetic retinopathy (1 ) and about 18 are of undetermined nature [1]. The repo.