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Anticancer Res 25: 183191. 24. Xie BX, Zhang H, Wang J, Pang B, Wu RQ, et al. Analysis of differentially expressed genes in LNCaP prostate cancer progression model. J Androl 23115181 32: 170182. 25. Bisoffi M, Klima I, Gresko E, Durfee PN, Hines WC, et al. Expression profiles of androgen independent bone metastatic prostate cancer cells indicate up-regulation of the putative serine-threonine kinase GS3955. J Urol 172: 1145 1150. 26. Weischenfeldt J, Simon R, Feuerbach L, Schlangen K, Weichenhan D, et al. Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer. Cancer Cell 23: 159170. 27. Grasso CS, Wu YM, Robinson DR, Cao X, Dhanasekaran SM, et al. The mutational landscape of lethal castration-resistant prostate cancer. Nature 487: 239243. 28. Lindberg J, Mills IG, Klevebring D, Liu W, Neiman M, et al. The mitochondrial and autosomal mutation landscapes of prostate cancer. Eur Urol 63: 702708. 29. Lang GI, Parsons L, Gammie AE Mutation prices, spectra, and genomewide distribution of spontaneous mutations in mismatch repair deficient yeast. G3 three: 14531465. 30. Leach FS, Velasco A, Hsieh JT, Sagalowsky AI, McConnell JD The mismatch repair gene hMSH2 is mutated in the prostate cancer cell line LNCaP. J Urol 164: 18301833. 31. Chen Y, Wang J, Fraig MM, Metcalf J, Turner WR, et al. Defects of DNA mismatch repair in human prostate cancer. Cancer Res 61: 41124121. 32. Barbieri CE, Baca SC, Lawrence MS, Autophagy Demichelis F, Blattner M, et al. Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. Nat Genet 44: 685689. 33. Baca SC, Prandi D, Lawrence MS, Mosquera JM, Romanel A, et al. Punctuated evolution of prostate cancer genomes. Cell 153: 666677. 34. Berger MF, Lawrence MS, Demichelis F, Drier Y, Cibulskis K, et al. The genomic complexity of key human prostate cancer. Nature 470: 214220. 35. Schuster-Bockler B, Lehner B Chromatin organization is often a big influence on regional mutation rates in human cancer cells. Nature 488: 504 507. 36. Fujita A, Gomes LR, Sato JR, Yamaguchi R, Thomaz CE, 17493865 et al. Multivariate gene expression analysis reveals functional connectivity modifications between normal/tumoral prostates. BMC Syst Biol 2: 106. 37. Tohtong R, Phattarasakul K, Jiraviriyakul A, Sutthiphongchai T Dependence of metastatic cancer cell invasion on MLCK-catalyzed phosphorylation of myosin regulatory light chain. Prostate Cancer Prostatic Dis 6: 212 216. 38. Niggli V, Schmid M, Nievergelt A Differential roles of Rho-kinase and myosin light chain kinas.Iu X, Han S, Wang Z, Gelernter J, Yang BZ Variant callers for nextgeneration sequencing data: a comparison study. PLoS A single 8: e75619. 20. Fu Z, Dozmorov IM, Keller ET Osteoblasts create soluble variables that induce a gene expression pattern in non-metastatic prostate cancer cells, related to that identified in bone metastatic prostate cancer cells. Prostate 51: 1020. 21. Liu AY, Brubaker KD, Goo YA, Quinn JE, Kral S, et al. Lineage relationship between LNCaP and LNCaP-derived prostate cancer cell lines. Prostate 60: 98108. 22. Oudes AJ, Roach JC, Walashek LS, Eichner LJ, True LD, et al. Application of Affymetrix array and Massively Parallel Signature Sequencing for identification of genes involved in prostate cancer progression. BMC Cancer 5: 86. 23. Trojan L, Schaaf A, Steidler A, Haak M, Thalmann G, et al. Identification of metastasis-associated genes in prostate cancer by genetic profiling of human prostate cancer cell lines. Anticancer Res 25: 183191. 24. Xie BX, Zhang H, Wang J, Pang B, Wu RQ, et al. Analysis of differentially expressed genes in LNCaP prostate cancer progression model. J Androl 23115181 32: 170182. 25. Bisoffi M, Klima I, Gresko E, Durfee PN, Hines WC, et al. Expression profiles of androgen independent bone metastatic prostate cancer cells indicate up-regulation of your putative serine-threonine kinase GS3955. J Urol 172: 1145 1150. 26. Weischenfeldt J, Simon R, Feuerbach L, Schlangen K, Weichenhan D, et al. Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer. Cancer Cell 23: 159170. 27. Grasso CS, Wu YM, Robinson DR, Cao X, Dhanasekaran SM, et al. The mutational landscape of lethal castration-resistant prostate cancer. Nature 487: 239243. 28. Lindberg J, Mills IG, Klevebring D, Liu W, Neiman M, et al. The mitochondrial and autosomal mutation landscapes of prostate cancer. Eur Urol 63: 702708. 29. Lang GI, Parsons L, Gammie AE Mutation prices, spectra, and genomewide distribution of spontaneous mutations in mismatch repair deficient yeast. G3 three: 14531465. 30. Leach FS, Velasco A, Hsieh JT, Sagalowsky AI, McConnell JD The mismatch repair gene hMSH2 is mutated within the prostate cancer cell line LNCaP. J Urol 164: 18301833. 31. Chen Y, Wang J, Fraig MM, Metcalf J, Turner WR, et al. Defects of DNA mismatch repair in human prostate cancer. Cancer Res 61: 41124121. 32. Barbieri CE, Baca SC, Lawrence MS, Demichelis F, Blattner M, et al. Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. Nat Genet 44: 685689. 33. Baca SC, Prandi D, Lawrence MS, Mosquera JM, Romanel A, et al. Punctuated evolution of prostate cancer genomes. Cell 153: 666677. 34. Berger MF, Lawrence MS, Demichelis F, Drier Y, Cibulskis K, et al. The genomic complexity of primary human prostate cancer. Nature 470: 214220. 35. Schuster-Bockler B, Lehner B Chromatin organization is often a major influence on regional mutation rates in human cancer cells. Nature 488: 504 507. 36. Fujita A, Gomes LR, Sato JR, Yamaguchi R, Thomaz CE, 17493865 et al. Multivariate gene expression analysis reveals functional connectivity alterations among normal/tumoral prostates. BMC Syst Biol 2: 106. 37. Tohtong R, Phattarasakul K, Jiraviriyakul A, Sutthiphongchai T Dependence of metastatic cancer cell invasion on MLCK-catalyzed phosphorylation of myosin regulatory light chain. Prostate Cancer Prostatic Dis six: 212 216. 38. Niggli V, Schmid M, Nievergelt A Differential roles of Rho-kinase and myosin light chain kinas.