Product Name :
KRAS G12C inhibitor 5
Description:
KRAS G12C inhibitor 5 is a KRas G12C inhibitor extracted from patent WO2017201161A1, Compound example 147.
CAS:
2158297-63-1
Molecular Weight:
551.68
Formula:
C32H37N7O2
Chemical Name:
2-[(2S)-4-(2-[(2S)-1-methylpyrrolidin-2-yl]methoxy-7-(naphthalen-1-yl)-5H,6H,7H,8H-pyrido[3,4-d]pyrimidin-4-yl)-1-(prop-2-enoyl)piperazin-2-yl]acetonitrile
Smiles :
CN1CCC[C@H]1COC1N=C2CN(CCC2=C(N=1)N1C[C@H](CC#N)N(CC1)C(=O)C=C)C1C=CC=C2C=CC=CC2=1
InChiKey:
OBKBMFMBHWUYHS-DQEYMECFSA-N
InChi :
InChI=1S/C32H37N7O2/c1-3-30(40)39-19-18-38(20-24(39)13-15-33)31-27-14-17-37(29-12-6-9-23-8-4-5-11-26(23)29)21-28(27)34-32(35-31)41-22-25-10-7-16-36(25)2/h3-6,8-9,11-12,24-25H,1,7,10,13-14,16-22H2,2H3/t24-,25-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
KRAS G12C inhibitor 5 is a KRas G12C inhibitor extracted from patent WO2017201161A1, Compound example 147.Folinic acid Biological Activity |Product information|CAS Number: 2158297-63-1|Molecular Weight: 551.68|Formula: C32H37N7O2|Chemical Name: 2-[(2S)-4-(2-[(2S)-1-methylpyrrolidin-2-yl]methoxy-7-(naphthalen-1-yl)-5H,6H,7H,8H-pyrido[3,4-d]pyrimidin-4-yl)-1-(prop-2-enoyl)piperazin-2-yl]acetonitrile|Smiles: CN1CCC[C@H]1COC1N=C2CN(CCC2=C(N=1)N1C[C@H](CC#N)N(CC1)C(=O)C=C)C1C=CC=C2C=CC=CC2=1|InChiKey: OBKBMFMBHWUYHS-DQEYMECFSA-N|InChi: InChI=1S/C32H37N7O2/c1-3-30(40)39-19-18-38(20-24(39)13-15-33)31-27-14-17-37(29-12-6-9-23-8-4-5-11-26(23)29)21-28(27)34-32(35-31)41-22-25-10-7-16-36(25)2/h3-6,8-9,11-12,24-25H,1,7,10,13-14,16-22H2,2H3/t24-,25-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Eflornithine MedChemExpress |Shelf Life: ≥12 months if stored properly.PMID:33021126 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|Kirsten Rat Sarcoma 2 Viral Oncogene Homolog (KRas) is a small GTPase and a member of the Ras family of oncogenes. KRas serves a molecular switch cycling between inactive (GDP -bound) and active (GTP -bound) states to transduce upstream cellular signals received from multiple tyrosine kinases to downstream effectors to regulate a wide variety of processes, including cellular proliferation.|Products are for research use only. Not for human use.|
