Product Name :
Propargyl-PEG6-Br
Description:
Propargyl-PEG6-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
1973383-30-0
Molecular Weight:
383.28
Formula:
C15H27BrO6
Chemical Name:
1-bromo-3,6,9,12,15,18-hexaoxahenicos-20-yne
Smiles :
C#CCOCCOCCOCCOCCOCCOCCBr
InChiKey:
VADSRAOHGSOPAQ-UHFFFAOYSA-N
InChi :
InChI=1S/C15H27BrO6/c1-2-4-17-6-8-19-10-12-21-14-15-22-13-11-20-9-7-18-5-3-16/h1H,3-15H2
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Propargyl-PEG6-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 1973383-30-0|Molecular Weight: 383.28|Formula: C15H27BrO6|Chemical Name: 1-bromo-3,6,9,12,15,18-hexaoxahenicos-20-yne|Smiles: C#CCOCCOCCOCCOCCOCCOCCBr|InChiKey: VADSRAOHGSOPAQ-UHFFFAOYSA-N|InChi: InChI=1S/C15H27BrO6/c1-2-4-17-6-8-19-10-12-21-14-15-22-13-11-20-9-7-18-5-3-16/h1H,3-15H2|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Rosuvastatin In stock |Shelf Life: ≥12 months if stored properly.1-(4-Bromophenyl)piperazine Autophagy |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32432445 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|References:| An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 Products are for research use only. Not for human use.|
