Product Name :
ZSTK474
Sequence:
Purity:
≥98% (HPLC)
Molecular Weight:
417.4
Solubility :
Soluble in DMSO (21mg/ml). Sparingly soluble in ethanol (
Appearance:
White powder.
Use/Stability :
As indicated on product label or CoA when stored as recommended. Stock solutions are stable for up to 6 months when stored at -20°C.
Description:
Inhibits all four PI3K isoforms.649749-10-0 custom synthesis Cell permeable, reversible, potent and specific inhibitor of phosphoinositide 3-kinase (IC50=17nM for PI(3)K p110β, IC50=53nM for PI(3)K p110γ and IC50=6nM for PI(3)K p110δ).143851-98-3 custom synthesis Blocks cellular PI(3)K/Akt (PKB) signalling in vitro and inhibits Akt(PKB)-dependent tumor growth in mice in vivo without significant toxic effect.PMID:28846231 More effective than LY 294,002 in vitro and as in vivo.
CAS :
475110-96-4
Solubility:
Soluble in DMSO (21mg/ml). Sparingly soluble in ethanol (
Formula:
C19H21F2N7O2
Additional Information :
| Alternative Name 2-(2-Difluoromethylbenzimidazol-1-yl)-4,6-dimorpholino-1,3,5-triazine | Appearance White powder. | CAS 475110-96-4 | Couple Target PI3 kinase | Couple Type Inhibitor | Formula C19H21F2N7O2 | Identity Determined by EM-MS and NMR. | MW 417.4 | Purity ≥98% (HPLC) | Solubility Soluble in DMSO (21mg/ml). Sparingly soluble in ethanol ( | Unit of Measure (UM) mg
