Product Name :
XAV939
Sequence:
Purity:
≥98% (HPLC)
Molecular Weight:
312.3
Solubility :
Soluble in DMSO (20 mg/ml).
Appearance:
White solid.
Use/Stability :
As indicated on product label or CoA when stored as recommended.2557349-50-3 site
Description:
PARP5a inhibitor Potent inhibitor of Tankyrase 1 (IC50=11nM) and Tankyrase 2 (IC50=4nM).1898283-02-7 site Inhibition of tankyrase promotes stabilization of axin resulting in β-catenin degradation and Wnt signalling disruption.PMID:20301446 Inhibits proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1. Promotes cardiomyogenic development in mesoderm progenitor cells.
CAS :
284028-89-3
Solubility:
Soluble in DMSO (20 mg/ml).
Formula:
C14H11F3N2OS
Additional Information :
| Alternative Name 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one | Appearance White solid. | CAS 284028-89-3 | Couple Target PARP | Couple Type Inhibitor | Formula C14H11F3N2OS | MW 312.3 | Purity ≥98% (HPLC) | Solubility Soluble in DMSO (20 mg/ml). | Unit of Measure (UM) mg
