Product Name :
NY2267
Description:
NY2267 is a disruptor of Myc-Max interaction, with an IC50 of 36.5 μM. NY2267 inhibits Myc- and Jun-induced transcriptional activation.
CAS:
886053-73-2
Molecular Weight:
637.76
Formula:
C38H43N3O6
Chemical Name:
tert-butyl 2-(6-[(cyclohexylcarbamoyl)(N-[(4-methoxyphenyl)methyl]-1-(pyridin-2-yl)formamido)methyl]naphthalen-2-yloxy)acetate
Smiles :
COC1C=CC(CN(C(C2=CC3=CC=C(C=C3C=C2)OCC(=O)OC(C)(C)C)C(=O)NC2CCCCC2)C(=O)C2=CC=CC=N2)=CC=1
InChiKey:
RVGDACCXDZIPOB-UHFFFAOYSA-N
InChi :
InChI=1S/C38H43N3O6/c1-38(2,3)47-34(42)25-46-32-20-17-27-22-29(16-15-28(27)23-32)35(36(43)40-30-10-6-5-7-11-30)41(37(44)33-12-8-9-21-39-33)24-26-13-18-31(45-4)19-14-26/h8-9,12-23,30,35H,5-7,10-11,24-25H2,1-4H3,(H,40,43)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Fruquintinib manufacturer
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
NY2267 is a disruptor of Myc-Max interaction, with an IC50 of 36.5 μM. NY2267 inhibits Myc- and Jun-induced transcriptional activation.|Product information|CAS Number: 886053-73-2|Molecular Weight: 637.76|Formula: C38H43N3O6|Chemical Name: tert-butyl 2-(6-[(cyclohexylcarbamoyl)(N-[(4-methoxyphenyl)methyl]-1-(pyridin-2-yl)formamido)methyl]naphthalen-2-yloxy)acetate|Smiles: COC1C=CC(CN(C(C2=CC3=CC=C(C=C3C=C2)OCC(=O)OC(C)(C)C)C(=O)NC2CCCCC2)C(=O)C2=CC=CC=N2)=CC=1|InChiKey: RVGDACCXDZIPOB-UHFFFAOYSA-N|InChi: InChI=1S/C38H43N3O6/c1-38(2,3)47-34(42)25-46-32-20-17-27-22-29(16-15-28(27)23-32)35(36(43)40-30-10-6-5-7-11-30)41(37(44)33-12-8-9-21-39-33)24-26-13-18-31(45-4)19-14-26/h8-9,12-23,30,35H,5-7,10-11,24-25H2,1-4H3,(H,40,43)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 250 mg/mL (392.Otamixaban Protocol 00 mM; Need ultrasonic and warming)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:33327922 |Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|NY2267 strongly inhibits oncogenic transformation induced by Myc.|References:|Yang Xu,et al. A credit-card library approach for disrupting protein-protein interactions. Bioorg Med Chem. 2006 Apr 15;14(8):2660-73.Products are for research use only. Not for human use.|
