Product Name :
Escin
Description:
Escin, a natural compound of triterpenoid saponins isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent.
CAS:
6805-41-0
Molecular Weight:
1131.26
Formula:
C55H86O24
Chemical Name:
(2S, 3S, 4S, 5R, 6R)-6-[(3S, 4S, 4aR, 6aR, 6bS, 8R, 8aR, 9R, 10R, 12aS, 14aR, 14bR)-9-(acetyloxy)-8-hydroxy-4, 8a-bis(hydroxymethyl)-4, 6a, 6b, 11, 11, 14b-hexamethyl-10-[(2E)-2-methylbut-2-enoyl]oxy-1, 2, 3, 4, 4a, 5, 6, 6a, 6b, 7, 8, 8a, 9, 10, 11, 12, 12a, 14, 14a, 14b-icosahydropicen-3-yl]oxy-4-hydroxy-3-[(2R, 3S, 4R, 5R, 6S)-3, 4, 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-[(2S, 3R, 4S, 5S)-3, 4, 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-2-carboxylic acid
Smiles :
CC1(C)C[C@H]2C3=CC[C@@H]4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@H]7O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]7O)[C@H](O)[C@H]6O[C@@H]6OC(CO)[C@@H](O)[C@H](O)[C@H]6O)C(O)=O)[C@](C)(CO)[C@@H]5CC[C@@]4(C)[C@]3(C)C[C@@H](O)[C@@]2(CO)[C@@H](OC(C)=O)[C@@H]1OC(=O)/C(/C)=C/C
InChiKey:
AXNVHPCVMSNXNP-BTGSHYACSA-N
InChi :
InChI=1S/C55H86O24/c1-10-23(2)46(71)79-43-44(72-24(3)60)55(22-59)26(17-50(43,4)5)25-11-12-30-51(6)15-14-32(52(7,21-58)29(51)13-16-53(30,8)54(25,9)18-31(55)61)75-49-41(77-48-38(67)36(65)34(63)28(20-57)74-48)39(68)40(42(78-49)45(69)70)76-47-37(66)35(64)33(62)27(19-56)73-47/h10-11,26-44,47-49,56-59,61-68H,12-22H2,1-9H3,(H,69,70)/b23-10+/t26-,27-,28?,29+,30+,31+,32-,33-,34+,35+,36-,37-,38+,39-,40-,41+,42-,43-,44-,47+,48-,49+,51-,52+,53+,54+,55-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Escin, a natural compound of triterpenoid saponins isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent.|Product information|CAS Number: 6805-41-0|Molecular Weight: 1131.26|Formula: C55H86O24|Chemical Name: (2S, 3S, 4S, 5R, 6R)-6-[(3S, 4S, 4aR, 6aR, 6bS, 8R, 8aR, 9R, 10R, 12aS, 14aR, 14bR)-9-(acetyloxy)-8-hydroxy-4, 8a-bis(hydroxymethyl)-4, 6a, 6b, 11, 11, 14b-hexamethyl-10-[(2E)-2-methylbut-2-enoyl]oxy-1, 2, 3, 4, 4a, 5, 6, 6a, 6b, 7, 8, 8a, 9, 10, 11, 12, 12a, 14, 14a, 14b-icosahydropicen-3-yl]oxy-4-hydroxy-3-[(2R, 3S, 4R, 5R, 6S)-3, 4, 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-[(2S, 3R, 4S, 5S)-3, 4, 5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-2-carboxylic acid|Smiles: CC1(C)C[C@H]2C3=CC[C@@H]4[C@@]5(C)CC[C@H](O[C@@H]6O[C@@H]([C@@H](O[C@H]7O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]7O)[C@H](O)[C@H]6O[C@@H]6OC(CO)[C@@H](O)[C@H](O)[C@H]6O)C(O)=O)[C@](C)(CO)[C@@H]5CC[C@@]4(C)[C@]3(C)C[C@@H](O)[C@@]2(CO)[C@@H](OC(C)=O)[C@@H]1OC(=O)/C(/C)=C/C|InChiKey: AXNVHPCVMSNXNP-BTGSHYACSA-N|InChi: InChI=1S/C55H86O24/c1-10-23(2)46(71)79-43-44(72-24(3)60)55(22-59)26(17-50(43,4)5)25-11-12-30-51(6)15-14-32(52(7,21-58)29(51)13-16-53(30,8)54(25,9)18-31(55)61)75-49-41(77-48-38(67)36(65)34(63)28(20-57)74-48)39(68)40(42(78-49)45(69)70)76-47-37(66)35(64)33(62)27(19-56)73-47/h10-11,26-44,47-49,56-59,61-68H,12-22H2,1-9H3,(H,69,70)/b23-10+/t26-,27-,28?,29+,30+,31+,32-,33-,34+,35+,36-,37-,38+,39-,40-,41+,42-,43-,44-,47+,48-,49+,51-,52+,53+,54+,55-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (88.Dabigatran In Vivo 40 mM; Need ultrasonic) H2O : Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Umeclidinium Data Sheet |Shelf Life: ≥360 days if stored properly.PMID:33346374 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Sipos W, et al. Escin inhibits type I allergic dermatitis in a novel porcine model. Int Arch Allergy Immunol. 2013;161(1):44-52.Products are for research use only. Not for human use.|
