Product Name :
UMB68 sodium
Description:
UMB68 sodium is a selective GHB receptor ligand. UMB68 sodium displaces [3H]NCS-382 with an IC50 of 38 nM in rat cerebrocortical membranes. UMB68 sodium has no significant affinity at GABAB receptors, cannot be metabolized to GABA-active compounds.
CAS:
581099-89-0
Molecular Weight:
154.14
Formula:
C6H11NaO3
Chemical Name:
sodium 4-hydroxy-4-methylpentanoate
Smiles :
[Na+].CC(C)(O)CCC([O-])=O
InChiKey:
RKKDHFJDHVHVLY-UHFFFAOYSA-M
InChi :
InChI=1S/C6H12O3.Na/c1-6(2,9)4-3-5(7)8;/h9H,3-4H2,1-2H3,(H,7,8);/q;+1/p-1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.{{Medroxyprogesterone} MedChemExpress|{Medroxyprogesterone} Progesterone Receptor|{Medroxyprogesterone} Biological Activity|{Medroxyprogesterone} In Vivo|{Medroxyprogesterone} manufacturer|{Medroxyprogesterone} Cancer}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Pacritinib} medchemexpress|{Pacritinib} JAK|{Pacritinib} Technical Information|{Pacritinib} In Vivo|{Pacritinib} custom synthesis|{Pacritinib} Epigenetics}
Additional information:
UMB68 sodium is a selective GHB receptor ligand.PMID:32240076 UMB68 sodium displaces [3H]NCS-382 with an IC50 of 38 nM in rat cerebrocortical membranes. UMB68 sodium has no significant affinity at GABAB receptors, cannot be metabolized to GABA-active compounds.|Product information|CAS Number: 581099-89-0|Molecular Weight: 154.14|Formula: C6H11NaO3|Chemical Name: sodium 4-hydroxy-4-methylpentanoate|Smiles: [Na+].CC(C)(O)CCC([O-])=O|InChiKey: RKKDHFJDHVHVLY-UHFFFAOYSA-M|InChi: InChI=1S/C6H12O3.Na/c1-6(2,9)4-3-5(7)8;/h9H,3-4H2,1-2H3,(H,7,8);/q;+1/p-1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|UMB68 inhibits [3H]NCS382 (16 nM) binding to the rat cerebrocortical membranes, with an IC50 of 38 nM compared with 25 μM for GHB. UMB68 shows no affinity (IC50 >100 μM) at GABA(A) or GABA(B) receptors.|In Vivo:|UMB68 (320-1778 mg/kg; i.p.) decreases markedly lever pressing in rats.|Products are for research use only. Not for human use.|
