Product Name :
PAC-1
Description:
PAC-1 is known as VO-100 and procaspase activating compound-1; which selectively induces apoptosis, or cell suicide, in cancerous cells. PAC-1 has shown good results in mouse models and is being further evaluated for use in humans. In 2010 a published study showed PAC-1 to be safe to research dogs, and a second study published later that same year reported that a PAC-1 derivative (called S-PAC-1) was well tolerated in a small Phase I Clinical Trial of pet dogs with lymphoma. Even at low doses of S-PAC-1, tumors regressed in 1/6 dogs, and the disease was stabilized (no additional tumor growth) in 3/6 dogs.
CAS:
315183-21-2
Molecular Weight:
392.49
Formula:
C23H28N4O2
Chemical Name:
2-(4-benzylpiperazin-1-yl)-N’-{[2-hydroxy-3-(prop-2-en-1-yl)phenyl]methylidene}acetohydrazide
Smiles :
C=CCC1=CC=CC(C=NNC(=O)CN2CCN(CC3C=CC=CC=3)CC2)=C1O
InChiKey:
YQNRVGJCPCNMKT-LFVJCYFKSA-N
InChi :
InChI=1S/C23H28N4O2/c1-2-7-20-10-6-11-21(23(20)29)16-24-25-22(28)18-27-14-12-26(13-15-27)17-19-8-4-3-5-9-19/h2-6,8-11,16,29H,1,7,12-15,17-18H2,(H,25,28)/b24-16+
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
PAC-1 is known as VO-100 and procaspase activating compound-1; which selectively induces apoptosis, or cell suicide, in cancerous cells. PAC-1 has shown good results in mouse models and is being further evaluated for use in humans. In 2010 a published study showed PAC-1 to be safe to research dogs, and a second study published later that same year reported that a PAC-1 derivative (called S-PAC-1) was well tolerated in a small Phase I Clinical Trial of pet dogs with lymphoma. Even at low doses of S-PAC-1, tumors regressed in 1/6 dogs, and the disease was stabilized (no additional tumor growth) in 3/6 dogs.|Product information|CAS Number: 315183-21-2|Molecular Weight: 392.{{Evenamide} medchemexpress|{Evenamide} Membrane Transporter/Ion Channel|{Evenamide} Technical Information|{Evenamide} In stock|{Evenamide} supplier|{Evenamide} Cancer} 49|Formula: C23H28N4O2|Chemical Name: 2-(4-benzylpiperazin-1-yl)-N’-{[2-hydroxy-3-(prop-2-en-1-yl)phenyl]methylidene}acetohydrazide|Smiles: C=CCC1=CC=CC(C=NNC(=O)CN2CCN(CC3C=CC=CC=3)CC2)=C1O|InChiKey: YQNRVGJCPCNMKT-LFVJCYFKSA-N|InChi: InChI=1S/C23H28N4O2/c1-2-7-20-10-6-11-21(23(20)29)16-24-25-22(28)18-27-14-12-26(13-15-27)17-19-8-4-3-5-9-19/h2-6,8-11,16,29H,1,7,12-15,17-18H2,(H,25,28)/b24-16+|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{SKF 81297} MedChemExpress|{SKF 81297} Agonist|{SKF 81297} Epigenetics|{SKF 81297} Purity & Documentation|{SKF 81297} Description|{SKF 81297} custom synthesis} |Shelf Life: ≥360 days if stored properly.PMID:23865629 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
