Product Name :
Sanguisorbigenin
Description:
Sanguisorbigenin is a natural antibacterial agent that inhibits methicillin-resistant S. aureus (MRSA).
CAS:
6812-98-2
Molecular Weight:
454.68
Formula:
C30H46O3
Chemical Name:
10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a-carboxylic acid
Smiles :
CC1(C)C2CCC3(C)C(CC=C4C5C(C)=C(C)CCC5(CCC34C)C(O)=O)C2(C)CCC1O
InChiKey:
HKJOHXSLBNLQHF-UHFFFAOYSA-N
InChi :
InChI=1S/C30H46O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,21-24,31H,9-17H2,1-7H3,(H,32,33)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Sanguisorbigenin is a natural antibacterial agent that inhibits methicillin-resistant S. aureus (MRSA).|Product information|CAS Number: 6812-98-2|Molecular Weight: 454.68|Formula: C30H46O3|Chemical Name: 10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydropicene-4a-carboxylic acid|Smiles: CC1(C)C2CCC3(C)C(CC=C4C5C(C)=C(C)CCC5(CCC34C)C(O)=O)C2(C)CCC1O|InChiKey: HKJOHXSLBNLQHF-UHFFFAOYSA-N|InChi: InChI=1S/C30H46O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,21-24,31H,9-17H2,1-7H3,(H,32,33)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Chloramphenicol} site|{Chloramphenicol} Autophagy|{Chloramphenicol} Technical Information|{Chloramphenicol} References|{Chloramphenicol} custom synthesis|{Chloramphenicol} Epigenetics} |Shelf Life: ≥12 months if stored properly.{{Tabalumab} medchemexpress|{Tabalumab} Apoptosis|{Tabalumab} Technical Information|{Tabalumab} Data Sheet|{Tabalumab} manufacturer|{Tabalumab} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23626759 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|The minimal inhibitory concentration values of Sanguisorbigenin against six strains of S. aureus are in the range of 12.5-50 μg/mL. The expression of blaR1, mecA and blaZ is significantly inhibited in MRSA in a dose-dependent manner when it is treated with sub-MIC (1.56-6.25 μg/mL) concentrations of Sanguisorbigenin. Sanguisorbigenin remarkably reduces the gene expression of mecA. Sanguisorbigenin has a potent antibacterial effect and could effectively reverse the sense of antibiotics by inhibiting the mecA expression and decrease PBP2a expression.|Products are for research use only. Not for human use.|
