Product Name :
Clindamycin
Description:
Clindamycin is an oral protein synthesis inhibitory agent that has the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs). Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA). Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla).
CAS:
18323-44-9
Molecular Weight:
424.98
Formula:
C18H33ClN2O5S
Chemical Name:
(2S,4R)-N-[(1S,2S)-2-chloro-1-hydrogenio-1-[(2R,3R,4S,5R,6R)-2-hydrogenio-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide
Smiles :
C[C@H](Cl)[C@@H](NC(=O)[C@@H]1C[C@@H](CCC)CN1C)[C@H]1O[C@H](SC)[C@H](O)[C@@H](O)[C@H]1O
InChiKey:
KDLRVYVGXIQJDK-AWPVFWJPSA-N
InChi :
InChI=1S/C18H33ClN2O5S/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25)/t9-,10+,11-,12+,13-,14+,15+,16+,18+/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{EACC} MedChemExpress|{EACC} Autophagy|{EACC} Protocol|{EACC} In Vivo|{EACC} manufacturer|{EACC} Epigenetic Reader Domain}
Additional information:
Clindamycin is an oral protein synthesis inhibitory agent that has the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs).{{Erdafitinib} MedChemExpress|{Erdafitinib} Apoptosis|{Erdafitinib} Purity & Documentation|{Erdafitinib} In Vitro|{Erdafitinib} manufacturer|{Erdafitinib} Autophagy} Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA).PMID:23776646 Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla).|Product information|CAS Number: 18323-44-9|Molecular Weight: 424.98|Formula: C18H33ClN2O5S|Chemical Name: (2S,4R)-N-[(1S,2S)-2-chloro-1-hydrogenio-1-[(2R,3R,4S,5R,6R)-2-hydrogenio-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide|Smiles: C[C@H](Cl)[C@@H](NC(=O)[C@@H]1C[C@@H](CCC)CN1C)[C@H]1O[C@H](SC)[C@H](O)[C@@H](O)[C@H]1O|InChiKey: KDLRVYVGXIQJDK-AWPVFWJPSA-N|InChi: InChI=1S/C18H33ClN2O5S/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25)/t9-,10+,11-,12+,13-,14+,15+,16+,18+/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
