Product Name :
ADHP
Description:
ADHP is a fluorogenic peroxidase substrate (λex=530 nm, λem=590 nm).
CAS:
119171-73-2
Molecular Weight:
257.24
Formula:
C14H11NO4
Chemical Name:
1-(3,7-dihydroxy-10H-phenoxazin-10-yl)ethan-1-one
Smiles :
CC(=O)N1C2=CC=C(O)C=C2OC2=CC(O)=CC=C12
InChiKey:
PKYCWFICOKSIHZ-UHFFFAOYSA-N
InChi :
InChI=1S/C14H11NO4/c1-8(16)15-11-4-2-9(17)6-13(11)19-14-7-10(18)3-5-12(14)15/h2-7,17-18H,1H3
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Voxilaprevir} site|{Voxilaprevir} Metabolic Enzyme/Protease|{Voxilaprevir} Technical Information|{Voxilaprevir} References|{Voxilaprevir} supplier|{Voxilaprevir} Cancer}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
ADHP is a fluorogenic peroxidase substrate (λex=530 nm, λem=590 nm).|Product information|CAS Number: 119171-73-2|Molecular Weight: 257.24|Formula: C14H11NO4|Chemical Name: 1-(3,7-dihydroxy-10H-phenoxazin-10-yl)ethan-1-one|Smiles: CC(=O)N1C2=CC=C(O)C=C2OC2=CC(O)=CC=C12|InChiKey: PKYCWFICOKSIHZ-UHFFFAOYSA-N|InChi: InChI=1S/C14H11NO4/c1-8(16)15-11-4-2-9(17)6-13(11)19-14-7-10(18)3-5-12(14)15/h2-7,17-18H,1H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Ac4ManNAz} MedChemExpress|{Ac4ManNAz} {Biochemical Assay Reagents}|{Ac4ManNAz} Protocol|{Ac4ManNAz} Formula|{Ac4ManNAz} supplier|{Ac4ManNAz} Epigenetics} |Shelf Life: ≥12 months if stored properly.PMID:23600560 |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|To obtain the parameters Km and kcat for Compound I, two independent methods are used. Initially, the oxidation of ADHP using the injector functionality built-in to the fluorescence plate reader is studied. The auto-injector dispenses the H2O2 to initiate the reaction, as a means of generating a set of progress curves. Analysis for MPO-mediated oxidation of ADHP gives a Km of 31±4 μM and the kcat of 186± 6 s−1.The kobs also increases over the experimental range of ADHP concentrations from 1 to 80 μM and for the converse experiment holding substrate constant over 3 to 45 nM MPO. The apparent second order rate constant obtain from the slope of kobs against ADHP concentration Kappon is 2.1±0.2 mM/s.|Products are for research use only. Not for human use.|
