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Original ArticleDiffusion-weighted EPI- and HASTE-MRI and 18F-FDG-PET-CT early during chemoradiotherapy in sophisticated head and neck cancerCharlotte S. Schouten1, Remco de Bree1, Lisa van der Putten1, Daniel P. Noij2, Otto S. Hoekstra2, Emile F.I. Comans2, Birgit I. Witte3, Patricia A. Doornaert4, C. RenLeemans1, Jonas A. CastelijnsDepartment of Otolaryngology-Head and Neck Surgery, 2Department of Radiology and Nuclear Medicine, 3Department of Epidemiology andBiostatistics, 4Department of Radiation Oncology, VU University Healthcare Center, Amsterdam, the Netherlands Correspondence to: Prof. Dr. Jonas A. Castelijns. Division of Radiology and Nuclear Medicine, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands. E-mail: [email protected] problem: Diffusion-weighted MRI (DW-MRI) has possible to predict chemoradiotherapy (CRT) response in head and neck squamous cell carcinoma (HNSCC) and is typically performed utilizing echoplanar imaging (EPI). Nevertheless, EPI-DWI is susceptible to geometric distortions. Half-fourier acquisition single-shot turbo spin-echo (HASTE)-DWI could possibly be an alternative. This potential pilot study evaluates the prospective predictive worth of EPI- and HASTE-DWI and 18F-fluorodeoxyglucose PET-CT (18F-FDGPET-CT) early for the duration of CRT for locoregional outco.
