001). Using Kaplan-Meier, the estimate recurrence imply time (months) was considerably reduce in cancer-related VTE (18.7) than provoked (29.0) and unprovoked VTE (28.four, P .001 by the log-rank test). The estimate survival mean time (months) was considerably reduced in cancer-related VTE (21.eight) than in provoked (30.5) and unprovoked VTE (29.eight, P .001 by the log-rank test). Conclusions: The presence of active cancer and PE with or without having DVT were a statistically considerable risk factor for recurrence. Individuals who developed recurrent VTE had 7-fold greater mortality rate than patients with no recurrences.A. Repp1; C. Holmes1; T. Plante1; M. Cushman1; N. Zakai1University of Vermont Health-related Center, Burlington, United states of america; Baylor College of Medicine, Houston, United states of america; 3ChronicDisease Study Group, Minneapolis, Usa; 4University of Washington, Seattle, Usa Background: Venous thromboembolisms (VTEs) are largely preventable and currently there’s not a computable phenotype to quickly and accurately recognize VTE working with electronic health record (EHR) data. Computable phenotypes make it doable to rapidly recognize a condition without having manual chart abstraction. Aims: We sought to develop and validate an precise and reproducible computable phenotype for newly diagnosed VTE that may be present at admission (POA). Our purpose should be to differentiate VTE POA from VTE that is hospital acquired, previously diagnosed/treated, or miscoded. Techniques: We captured all admissions to the healthcare solutions involving 20109 in the University of Vermont Health-related Center. A computable phenotype for VTE was developed making use of International Classification of Illnesses (ICD) 9 or 10 discharge codes using the POA ERĪ± Agonist medchemexpress billing flag, present process terminology (CPT) codes for VTE-directed imaging research, and anticoagulant medication administration. The algorithm that was made was compared with all the gold standard for VTE POA – physician chart abstraction. 120 charts had been abstracted from five unique categories along with the sensitivity and CYP2 Activator site specificity of the computable phenotype vs. gold common was assessed working with survey weighting methodology. Results: For the 120 charts that have been abstracted for the computable phenotype, 71 charts had been marked as POA VTE by the computable phenotype and 63 of those had been confirmed as POA VTE with manual abstraction. Making use of survey weighting methodology to recreate the supply population, the VTE case definition had a specificity of 95.9 and a sensitivity of 99.6 (Table 1). TABLE 1 Weighted POA VTE information comparing physician chart abstraction plus the computable phenotypeConclusions: We developed a computable phenotype to determine POA VTE with excellent sensitivity and specificity. This could be made use of to additional define risk components for VTE utilizing EHR information and to differentiate VTE POA from hospital-acquired VTE.ABSTRACT883 of|PB1201|National Survey of Hospital ssociated Venous Thromboembolism Prevention in NHS England: Findings from the GIRFT Thrombosis SurveyPB1202|How Typical Are Uterine Venous Plexus Thrombi in Women Attending the Gynaecology Clinic T. Amin1; H. Cohen2; M. Wong2; D. JurkovicL.N. Roberts ; M. De Caro ; A.-M. Ridgeon ; C. Moroy ; T. Briggs B.J Hunt ; R. Arya1 54,;Guy’s and St Thomas’s NHS Foundation Trust, London, UnitedKingdom; 2University College London Hospitals NHS Foundations Trust, London, United kingdom Background: Venous thromboembolism (VTE) has been a major reason for direct maternal deaths in the U.K. for over two deca
