Vruch, J., C. Belham, Q. Weng, K. Hara, and K. Yonezawa. 2001. The p70 S6 2093388-62-4 Protocol kinase integrates nutrient and growth alerts to regulate translational capacity. Prog. Mol. Subcell. Biol. 26:11554. three. Brostrom, M. A., K. V. Chin, C. Cade, D. Gmitter, and C. O. Brostrom. 1987. Stimulation of protein synthesis in pituitary cells by phorbol esters and 1332331-08-4 supplier cyclic AMP. Evidence for rapid induction of the component of translational initiation. J. Biol. Chem. 262:165156523. four. Brown, E. J., P. A. Beal, C. T. Keith, J. Chen, T. B. Shin, and S. L. Schreiber. 1995. Regulate of p70 s6 kinase by kinase activity of FRAP in vivo. Mother nature 377:44146. 5. Brownawell, A. M., G. J. Kops, I. G. Macara, and B. M. Burgering. 2001. Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and exercise from the forkhead transcription aspect AFX. Mol. Mobile. Biol. 21:3534546. 6. Burgering, B. M., and P. J. Coffer. 1995. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase sign transduction. Character 376:59902. 7. Burnett, P. E., R. K. Barrow, N. A. Cohen, S. H. Darutoside supplier Snyder, and D. M. Sabatini. 1998. RAFT1 phosphorylation on the translational regulators p70 S6 kinase and 4E-BP1. Proc. Natl. Acad. Sci. United states of america 95:1432437. eight. Burnett, P. E., S. Blackshaw, M. M. Lai, I. A. Qureshi, A. F. Burnett, D. M. Sabatini, and S. H. Snyder. 1998. Neurabin is really a synaptic protein linking p70 S6 kinase along with the neuronal cytoskeleton. Proc. Natl. Acad. Sci. United states of america ninety five: 8351356. 9. Chou, M. M., and J. Blenis. 1996. The 70 kDa S6 kinase complexes with and is also activated by the Rho loved ones G proteins Cdc42 and Rac1. Mobile. eighty five:57383. ten. Chou, M. M., and J. Blenis. 1995. The 70 kDa S6 kinase: regulation of aVOL. 23,SUBCELLULAR LOCALIZATION OF S6K II IS Regulated BY PKC11. 12. 13. 14. 15. sixteen. seventeen. 18. 19.twenty.21.22. 23. 24. twenty five. 26. 27. 28.29. thirty. 31. 32. 33.34. 35.36. 37.kinase with numerous roles in mitogenic signalling. Curr. Opin. Cell Biol. 7:80614. Chung, J., T. C. Grammer, K. P. Lemon, A. Kazlauskas, and J. Blenis. 1994. PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase. Nature 370:715. Cramer, R., W. J. Richter, E. Stimson, and also a. L. Burlingame. 1998. Assessment of phospho- and glycopolypeptides with infrared matrix-assisted laser desorption and ionization. Anal. Chem. 70:4939944. de Groot, R. P., L. M. Ballou, and P. Sassone-Corsi. 1994. Favourable regulation on the cAMP-responsive activator CREM from the p70 S6 kinase: an alternative path to mitogen-induced gene expression. Cell 79:811. Dennis, P. B., N. Pullen, R. B. Pearson, S. C. Kozma, and G. Thomas. 1998. Phosphorylation internet sites inside the autoinhibitory domain take part in p70(s6k) activation loop phosphorylation. J. Biol. Chem. 273:148454852. Dufner, A., and G. Thomas. 1999. Ribosomal S6 kinase signaling as well as command of translation. Exp. Cell Res. 253:10009. Duncan, R., and E. H. McConkey. 1982. Preferential utilization of phosphorylated 40-S ribosomal subunits for the duration of initiation advanced formation. Eur. J. Biochem. 123:53538. Gorlich, D., and U. Kutay. 1999. Transportation in between the mobile nucleus and the cytoplasm. Annu. Rev. Mobile Dev. Biol. 15:60760. Gorlich, D., and i. W. Mattaj. 1996. Nucleocytoplasmic transport. Science 271:1513518. Gout, I., T. Minami, K. Hara, Y. Tsujishita, V. Filonenko, M. D. Waterfield, and K. Yonezawa. 1998. Molecular cloning and characterization of the novel p70 S6 kinase, p70 S6 kinase beta containing a proline-rich location. J. Biol. Chem. 273:300610064. Han,.