L and neurotrauma ICUs amongst February 2002 and September 2006. Before March 2004 the common ITU applied PPIs for all individuals as gastric acid prophylaxis, as well as the neurotrauma ITU applied PPIs for only sufferers at higher danger of GI ulceration. Following instigation of ventilator care bundles in March 2004 each units gave PPIs to all ventilated individuals. The incidence of C. Procyanidin B2 biological activity difficile toxin-positive samples along with the quantity of doses of PPI made use of every month were compared for before and immediately after this time period. The usage of antibiotics was also compared involving the two units more than the time period to exclude this as a confounding variable. Final results We identified 92 C. difficile-positive faecal samples through the 57-month period from February 2002 to September 2006. This averaged 1.61 cases monthly. The basic ITU (ITU2) presented 49 instances (53.2 ), plus the neurotrauma ITU (ITU3) 43 cases (46.8 ). In February 2002, PPI usage was infrequent inside the ITU3, but much more popular in ITU2. The C. difficile rates have been also larger in ITU2 than in ITU3. PPI usage improved in ITU3 till, around the instigation of your ventilator care bundle, PPIs have been utilized for all sufferers from March 2004. Our preliminary PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20799915 data demonstrate an increase in C. difficile rates in ITU3, to meet the rates of ITU2, in the very same time as PPI usage was increased (Figure 1). The ITUs back onto each other and share exactly the same health-related and nursing staff. Antibiotic usage was similar across both units with regards to cephalosporins, meropenem and pipracillin/tazobactam. Conclusion C. difficile prices have remained relatively stable around the common ITU (ITU2) but showed a significant raise on theP147 A study of enteral tube feeding in critically ill patientsA Holdsworth, T Rahman St George’s Hospital, London, UK Important Care 2007, 11(Suppl two):P147 (doi: 10.1186/cc5307) Introduction For critically ill sufferers unable to consume, enteral tube feeding (ETF) could be the preferred mode of feeding. The study aimed to investigate the quantity of enteral feed obtained by sufferers on ICU inside a busy London Teaching Hospital, the efficiency of initiation of feeding, and probable motives for the failure of your above. Procedures A prospective observational study was carried out more than 1 month on individuals admitted to a general and cardiothoracic ICU, who received ETF. Baseline data like age, reason for admission and illness severity score (SOFA) were documented. Length of time from admission to begin of feeding was noted, and the volume of feed delivered to individuals was recorded. The quantity of calories delivered to the patient was compared with the patient’s excellent nutritional requirement (determined by the ICU ETF protocol). Feeding interruptions had been also recorded.SCritical CareMarch 2007 Vol 11 Suppl27th International Symposium on Intensive Care and Emergency MedicineFigure 1 (abstract P148)between changing tracheostomy (suggesting repeat procedures) and subsequent difficulty swallowing. A single patient inside this group subsequently created a tracheal stenosis. See Table 1. Conclusion We located the percentage of sufferers reporting swallowing troubles post percutaneous tracheostomy (PCT) (Portex Blue Line Ultra tracheostomy tube) to be higher than one particular would count on. This might be confounded by neurological injury necessitating the need to get a PCT, but we feel this could be an region of concern meriting additional investigation provided frequent PCT in ICU practice.P150 Intestinal corticotropin-releasing issue is decreased in shocked trauma.
